What are some problems that can occur from an altered gene that makes hemoglobin?

The most common is the development of sickle cell anemia. This is as a result of a mutation in the hemoglobin gene that affects the beta polypeptide chain of the protein. This reduces HB’s affinity to oxygen. Other problems include Thalassaemia, Porphyria, and Carbon Monoxide Poisoning.

which fault and or fold did you find most difficult to diagram