Which mutation does the given change in nucleotide sequence represent? attgcatc → atacgttc

Substitution Mutation (Transversion)

Explanation:

In a substitution mutation, the complementary base pairs of a gene get substituted.  

Hence,a purine is substituted by a pyrimidine base or vice versa  happens

ATTGCATC → ATACGTTC

In this set of gene , the bold highlighted base “TGCA” is replaced by its complementary base pair “ACGT”

A is complementary to T

G is complementary to C

Hence , this mutation is a tranversion substitution mutation

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