How might a change of one amino acid at a site, distant from the active site of an enzyme, alter the substrate specificity of an enzyme? by changing the optimum ph for the enzyme by changing the stability of the enzyme by changing the binding site for a noncompetitive inhibitor by changing the three-dimensional conformation of the enzyme?

Ateam from new york presbyterian hospital is conducting a study about a recent increase in cases involving both excess sweating and kidney stones. what would the team need before it draws a conclusion about the cases? medications that are specifically designed to treat the sickness machines that are built to process blood and reduce symptoms until patients are healthy again data that profile the various patients who report these symptoms proof that the excess sweating is related to the excessive kidney stones