Based on the diathesis-stress model, which combination is associated with the highest potential for the development of schizophrenia?

Based on the ''diathesis-stress'' model the combination of the genetic traits combined with stress induced hormones such as the ''cortisol'' claims the highest potential for the development of schizophrenia

This theory is the one that gives a trajectory relationship between the vulnerability of a person to get the disease that may be due to biological, genetic or situational factors  with the environmental factors such as ''stress'' that plays a major role in developing the disorder such as ''schizophrenia''.