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Business, 27.11.2019 01:31 ILOVEAARON39821

How would signaling be affected if a mutation caused a g protein to replace gdp with gtp on its own without needing to be activated by the g protein-coupled receptor? the signal would not be affected and signaling would only occur when a ligand bound to the receptor. the signaling would be blocked because g protein would be active but unable to signal due to the lack of a bound ligand. the signaling pathway would be activated even when no ligand was present. the signaling would be blocked because replacement of gdp with gtp would deactivate the g protein.

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