Nucleophilic aromatic substitution is far less common than electrophilic aromatic substitution. however, there are examples of it. for example, sanger’s reagent (2,4-dinitrofluorobenzene) is capable of labeling the n-terminus (the amino terminus) of proteins. provide a mechanism for the labeling of the protein below with sanger’s reagent.
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Nucleophilic aromatic substitution is far less common than electrophilic aromatic substitution. howe...
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