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Chemistry, 17.12.2019 01:31 williamslyric

Low levels of certain types of estrogens in the body is the cause of several diseases in women. alora is an fda-approved drug for the treatment of symptoms associated with menopause and prevention of postmenopausal osteoporosis. the active ingredient in alora is 17β-estradiol (estradiol), an essential estrogen. the enzyme 17β-hydroxysteroid dehydrogenase (17β-hsd) converts estrone into estradiol in the body. as a medicinal chemist, how would you synthesize estradiol from estrone in the laboratory?

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