The michaelis-menten equation is an expression of the relationship between the initial velocity, v0, of an enzymatic reaction and substrate concentration, [s]. there are three conditions that are useful for simplifying the michaelis-menten equation to an expression from which the effect of [s] on the rate can be more readily determined. match the condition (e. g. [s] = km) with the statement(s) that describe it:

1. doubling [s] will almost double the rate.
2. half of the active sites are occupied by substrate.
3. about 90% of the active sites are occupied by substrate.
4. doubling [s] will have little effect on the rate.
5. less than 10% of the active sites are occupied by substrate.
6. this condition will result in the highest rate.