Which of the following statements about nadh and its effect on the citrate cycle are true? choose one or more:

a. high concentrations of nadh will lead to an increased amount of acetyl-coa being produced due to nadh activating the pyruvate dehydrogenase enzyme.

b. increasing nadh concentrations will inhibit the citrate cycle.

c. low concentrations of nadh will result in lower concentrations of a-ketoglutarate due to inhibition of the isocitrate dehydrogenase enzyme.

d. nadh will bind to the enzyme citrate synthase, and when there is significantly more nadh in the cell than nad+, less citrate will be produced.