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Chemistry, 09.04.2020 22:57 rk193140

The ΔG° ' of the reverse reaction is +31 kJ/mol (+7.5 kcal/mol) . Instead of reversing the pyruvate kinase reaction, the step is bypassed in gluconeogenesis. Several steps for the conversion of pyruvate to phosphoenolpyruvate via gluconeogenesis are given. Place the steps in the correct order. You will not place all of the steps.

a. In the mitochondrion. pyruvate carboxylase converts pyruvate to oxaboacetate.
b. Malate dehydrogenase in the cytoplasm oxidizes malate to oxaloacetate.
c. Phosphoenolpyruvate carboxykinase decarboxylates and phosphorylates oxaloacetate, forming phosphoenolpyruvate.
d. In the cytoplasm, pyruvate carboxylase converts pyruvate to oxaboacetate.
e. Pyruvate decarboxylase converts oxaloacetate to phosphoenolpyruvate.
f. Malate dehydrogenase in the mitochondrion reduces oxaloacetate to malate.

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