Chemistry, 05.05.2020 18:34 wrightstephanie193
G Consider the compound. This is pyridoxal phosphate (P L P) with several functional groups selected. P L P is a heterocyclic 6 membered ring. The first position is a nitrogen which is selected and labeled D. The carbon in the third position is bound a side chain C H 2 P O 4 2 minus. The phosphate group is selected and labeled A. The carbon in the third position is single bound to a C O H group. The C O H is selected and labeled B. The carbon in the fourth position is single bonded to an O H group. The O H group is selected and labeled C. The carbon in the fifth position is single bonded to an unselected methyl group. Identify the group in pyridoxal phosphate (PLP) that covalently binds enzyme and substrate. B D A C Aminotransferases (transaminases) must deaminate one amino acid and add an amino group to another amino acid during transamination. How do the two processes differ? The second part of the reaction (adding an amino group) is the reverse of the first (deamination). The second part of the reaction takes place at a separate amino acid residue in the active site. The coenzyme PLP must be activated by an external amino group before it can catalyze the removal of the amino group from the first amino acid. The first reaction involves the formation of a Schiff base, whereas the second does not.
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G Consider the compound. This is pyridoxal phosphate (P L P) with several functional groups selected...
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