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Chemistry, 21.10.2020 16:01 Jasten

The nucleophile is generated by an acid-base reaction between an acyl-substituted phenol and 5% aq. NaOH solution. Provide an electron-pushing mechanism for this reaction and use pKa values to clearly identify whether this reaction can be best represented as one-directional or an equilibrium. Finally, explain the impact of the acid-base reaction on the solubility of the nucleophile in aqueous and organic solutions

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