Chemistry, 19.11.2020 19:20 dontworry48
What is the benefit of substrate channeling? The PDH active site forms in the hydrophobic core of the complex instead of a surface‑exposed region. Reaction intermediates move to sequential active sites faster than the diffusion constant. Every intermediate or product made by the PDH complex enters the citric acid cycle as a substrate. The PDH complex sequesters excess substrate to use at later time. Intermediates of a multistep reaction sequence do not dissociate from the enzyme complex.
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What is the benefit of substrate channeling? The PDH active site forms in the hydrophobic core of th...
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