Which fact results from the presence of both polar and nonpolar side chains in a protein?

The fact results from the presence of both polar and nonpolar side chains in a protein is Water has a strong effect on tertiary structure.

While the fact doesn't results from the presence of both polar and nonpolar side chains in a protein are the below:

1.) Proteins ionize when they are placed in water.
2.) Each protein has many functions.
3.) A protein's folding doesn't depend on the polarity of the environment.
4.) pH has a strong effect on secondary structure.

Nonmetals usually react by gaining electrons