Predict the effect of each of the following mutations on the rate of glycolysis in liver cells:
a. Loss of the allosteric site for ATP in phosphofructokinase.
b. Loss of the phosphatase domain of the bifunctional enzyme that controls the level of fructose 2,6-bisphosphate
c. Loss of the binding site for fructose 1,6-bisphosphate in pyruvate kinase
d. Loss of the phosphatase domain of the bifunctional enzyme that controls the level of fructose 2,6-bisphosphate
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Predict the effect of each of the following mutations on the rate of glycolysis in liver cells:
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