Proteins are large biomolecules made up of strings of amino acids, which may have hydrophobic or hydrophilic side chains (commonly referred to as the amino acid R groups). Proteins fold into complex three dimensional shapes based in part on the sequence of those amino acid side chains. In globular proteins, water is often excluded from the core of the protein, just like water is excluded from the middle of a phospholipid bilayer. Which of the following is true about the relative position of hydrophilic and hydrophobic amino acids for globular protein structures in aqueous solutions? (select two answers) a. Hydrophobic amino acids should tend to be evenly distributed between the inner core and outer surface of proteins.
b. Hydrophilic amino acids should tend to be evenly distributed between the inner core and outer surface of proteins
c. Hydrophobic amino acids should tend to be found on the outer surface of proteins, facing the aqueous solvent.
d. Hydrophilic amino acids should tend to be found on the outer surface of proteins, facing the aqueous solvent.
e. Hydrophobic amino acids should tend to be found in the inner core of proteins.
f. Hydrophilic amino acids should tend to be found in the inner core of proteins