How do phospholipids interact with water molecules? how do phospholipids interact with water molecules? phospholipids dissolve in water. phospholipids do not interact with water because water is polar and lipids are nonpolar. the polar heads interact with water; the nonpolar tails do not. the polar heads avoid water; the nonpolar tails attract water (because water is polar and opposites attract)?

The answer is: The polar heads interact with water; the nonpolar tails do not.

Phospholipids are a class of lipids and a significant component of all cell membranes. They are amphipathic molecules which means that they have a head that is hydrophilic (attracts water) and a tail that is hydrophobic (it repels water). The hydrophilic head has a negatively charged phosphate group, which is polar and which makes it hydrophilic. The hydrophobic tail typically consists of long fatty acid carbonic hydrogen chains. As a result, phosphates in water always turn to water and fatty acids to each other. In this way, a bilayer of phospholipid is formed which in the construction of the cell membrane prevents the release of the liquid content.