What were some of the challenges to safety resulting from such radical airframe designs as highly swept wings, high wing loading, increasing speed, and long-duration flights are high altitude

Assuming compressible flow of air and that the measurements are done at flagstaff a pitot static tube that gives the difference of total and static pressure measures 0.35 m of mercury. what is the velocity of air? assume the temperature to be 300k. (submit your excel or matlab calculation sheet)