Me pleease > > > >
which is not a part of the process used to determine the meaning of an unfamiliar word?
replace with a synonym
leave out the unfamiliar word
think of an opposite word
look for context clues

I think the correct answer is the last one 
look for context clues

If you don't know this word, you can't find neither a synonym nor an opposite because you don't know what it means.
You can't just leave it out

so you have to find out by context clues, I guess ...

Hope I helped !