What are the advantages of using a pig’s heart to create a human heart versus growing a heart directly from stem cells?

Recently much interest has been centred towards the comparison of a pig’s heart and human heart in the pursuit of Xenotransplantation. This is because there has been a growing demand of organ transplantation which is unmet by the number of human donors . Although, both belong to the genera of Mammalian origin there are marked difference in the anatomy of their hearts and also their associated physiological functioning. Both the hearts are divided into the auricular and ventricular chambers and have their drainage through the pulmonary arteries and aorta into the lesser and greater circulation. The myocardial volume supplied by left coronary arteries are higher and dominant compared to right coronary arteries in both these hearts as the left heart needs more oxygen supply for its greater activity to pump blood into the systemic circulation .

Explanation:

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The human heart is a very intricate organ with a complex vessel system. So far, scientists have grown only simple tissues from stem cells. Using a pig’s heart provides a structure for new human cells to grow.

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