The Midwest is A . an inland region B. located on the Atlantic coast C. located on the Pacific coast D. a region that includes 4 states

A. an inland region

Explanation:

an inland region can be considered as a region that's far from the coast or in the middle of the country. so the "mid" in "midwest" is a good clue that this region is in the middle of the united states.

why the other options are not correct:

- the midwest is not on the pacific coast. otherwise it'd be more to the west and could be called the west coast.

- the midwest is not on the atlantic coast. otherwise it'd be more to the east and could be called the east coast.

- the midwest has more than 4 includes! it includes 12, such as illinois, michigan, indiana, wisconsin, and minnesota/