Health, 08.07.2019 16:00 gedntrxAa

Amuscle cramp is a sudden, painful contraction of a muscle, during which movement is difficult. what is happening at the cellular level during a muscle cramp?

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At the onset of a muscle contraction, the presence of calcium triggers the opening of the Na-K channels in the membrane. Potassium is a calcium inhibitor, so as the potassium flows out of the cell, it eventually reduces the presence of calcium. This causes the closure of the Na-K channel (negative feedback mechanism). In a hypokalemic state, the lack of sufficient K doesn't inhibit the calcium channel, and in turn doesn't properly terminate the muscle contraction at the cellular level.

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Answer from: Quest

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Amuscle cramp is a sudden, painful contraction of a muscle, during which movement is difficult. what...

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