Your good friend Margaret is currently within appropriate ranges for height and weight and body fat percentage, yet she thinks she is fat. Margaret is always talking negatively about herself. She exercises vigorously at least an hour every day, and sometimes twice a day. Sometimes she skips meals.

What concerns do you have about Margaret? What could you say or do to help her? Write at least one paragraph. (5 pts)

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for