You are caring for a 13-year-old girl. The mother is consulting with the physician in her office. Upon returning to the exam room you find the girl and her boyfriend in a heated discussion. You heard him calling her names, holding her by the wrist, and threatening her. What do you do?

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for