You're at a friend's house, and his parents are serving alcoholic drinks to the teenagers. you're not interested, but your friend and his parents try to convince you that it's okay to drink underage as long as there is an adult present. what is the best way to handle the situation?

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for: a. neither of the subjects b. subject 603 only c. subject 20 only d. both of the subjects

Jordan is now 19-years old. as an infant, jordan reached many gross motor skill milestones, such as holding his head up, rolling over, sitting, and standing, at normal times. however, he was considered a "late walker" because he took his first steps at 17 months. by 2 years old, his parents noticed a hyperlordotic posture while he was standing. a gower's sign and trendelenberg gait were noted by age four. throughout his childhood, he suffered progressive muscle weakness, especially in the proximal musculature of the arms, pelvis, and legs. he required orthotic braces to assist his walking and was confined to wheelchair ambulation by age 13. at 16, he was hospitalized with bronchitis requiring antibiotic treatment, but recovered. jordan has a history of progressive muscle weakness, but no history of muscle pain or spasm, chest pain, or irregular heartbeat. the only medications that he normally takes are calcium and fluoride supplements. jordan has three siblings. his older and younger sisters have never had any major medical issues. jordan's older brother is also to a wheelchair with problems similar to jordan's. no other immediate or distant family members have musculoskeletal issues.1. jordan’s history aligns most closely with which diagnosis? a. amyotrophic lateral sclerosisb. multiple sclerosisc. duchenne muscular dystrophyd. myotonic dystrophy2. jordan had a biopsy of the left gastrocnemius muscle when he was 5 years old. based on your answer for his diagnosis, describe the microscopic pathological changes that the pathologist would have noted.3. explain, in your own words, why jordan’s brother appears to have the same disease and why his sisters are unaffected.

Nina has the flu and a high fever. her immune system is exhibiting the line of defense. this defense is part of immunity.