What evidence do you have that changes to genetic information can hurt an organism?

Can someone me. so last night i was with my girl and i ended up with a peanut butter jar in my anus. sadly we have tried to pull it out but its well stuck in there : ( any ideas how to get it out?

Which of the following is also referred to as "swayback"? a. kyphosis b. scoliosis c. lordosis d. none of the above

How can the stress response be used in a way. for example to build resilience.