An example of the body's second line of defense against a pathogen is

The second line of defense is nonspecific resistance that destroys invaders in a generalized way without targeting specific individuals. Phagocytic cells ingest and destroy all microbes that pass into body tissues. For example macrophages are cells derived from monocytes a type of white blood cell.

Well if you pick a machine to work on and that's gonna be your exercise if you don't stick to that machine your muscle strength your muscle mass rather will change because you haven't been doing it you change something in your exercise routine which changes your body's form of dealing with things for example you might become weaker or stronger depending on what kind of exercises you do in whether or not the machine you picked actually your muscles grow.