An investigator is confronted with a life-threatening situation that necessitates using a test article in a human subject who is unable to provide informed consent and there is no time to obtain consent from the individual's LAR and no alternative method or recognized therapy is available. Under the FDA regulations for using test articles, which of the following describes the best course of action for the investigator.

Sleep paralysis. so this is something i’ve dealt with for most of my life (i’m 15) and i’m pretty sure my first sp was when i was 9. and it’s usually the usual i’m not able to move anything except for my eyes, and it’s so hard to breathe (feels like someone’s pushing hard on my chest) and then i hear someone whispering and then i can move and then have to essentially wake up because i won’t be able to go back to sleep. but recently. and i mean it’s happened twice now and it’s not even been a week. where i suddenly wake up like a noise woke me, but then soon realize i’m not able to move and i sleep on my side that doesn’t face the wall and i have a desk that is on the same wall as my bed but farther off in the room. and i see myself sitting in the computer chair. like me. but as soon as i see (myself) it spins around and faces me and just stares at me for a good 2-3 minutes. and then it is that i realize that it’s got cold eyes instead of my normal eyes. and for one it’s absolutely creepy to be able to see yourself move without you ya know and secondly i kinda feel threatened to be honest. it’s happened 2 times now and i noticed the 2nd time (me) stared at my paralyzed body for about a minute longer then the 1st time. i just wonder if anyone else experienced anything like this because i’ve never had this happen before. and i’ve told my close family and they just shrugged it off and said i’m just having bad dreams again, but my computer chair is facing my bed when i come back into my room? and i know usually these are hallucinations but nothing’s changed in my life to cause a sudden anxiety or stress spell so i don’t know. and i know what bad dreams feel like and sp is waay worse then a bad dream. you can’t be awake to be having a bad dream

Which of the following is an argument against buying local fruits and vegetables?

A27 year old female client, who weighs 130 lb, claims to be able to lift 85 lb for 10 repetitions on the bench but only completed 6 repetitions. using the correct response for your client's 1 repetition max for bench press, what would her perceived rating be with regards to bench press strength?