What was the largest killer of the native americans on the islands

I think Christopher Columbus because Christopher Columbus killed the native Americans and he had murdered them when they welcome him then he send his people to killed the native Americans. Hope that help

Search it up i really dk

The transcontinental railroad provided a means of fast transportation. it cut a 6 month trip into 6 days, created jobs for many people and encouraged immigration. the homestead act played a huge role in western expansion; it allowed settlers to begin a fresh start, and gave them land in exchange for their residence for up to five years and a small fee.