What major policy issue divided the federalists and democratic-republicans until 1816?

The policy was often referred to as the  Hartford Convention. Where Federalists opposed to the War of 1812 tried to have New England secede from the country. And the Democrat-Republicans became the only viable political party, James Monroe won the 1816 election with 80 percent of the vote and the Era of Good Feelings began.

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the articles of confederation placed most of the power on the feds

here are some major conflicts i found. maybe pick one and do more research on it. (cause i ain't writing 6 paragraphs)

in 1877, the nez perce war took place.

1881 - president james garfield was assassinated.

1882 - the chinese exclusion act was passed.

1883 - a decision in the civil rights cases legalized racial segregation in the united states.

1887 - the dawes act was passed.

1893 - the panic of 1893 took place. (what a creative name)

and there are probably other topics you can find if you just search up "united states timeline," or "conflicts in the 19th century for america."

then once you find a topic you like find out how it affected the people of america and what not. (sorry if this feels a bit short changed, history was and never will be one of my strong topics)