Which major city in the soviet union suffered under germany’s blockade?

Leningrad suffered the most under Germany's blockade

The major city in the Soviet Union that suffered under Germany's blockade is Leningrad. The Siege of Leningrad began on the 8th of September in 1941 and ended on the 27th of January of 1944 following the retreat of the Wehrmacht. Hope this helps! ~ Autumn :)