What was the significance of the massacre at wounded knee?
a) it led directly to the passage of the dawes act of 1887.
b) it marked the end of indian resistance to the united states government.
c) it marked the beginning of a massive wave of combat between the u. s. military and the sioux nation.
d) the united states government passed legislation to prohibit the use of violence against native americans.

B) It marked the end of Indian resistance to the United States government.

Explanation:

The battle between U.S. military troops and Lakota Sioux Indians at Wounded Knee Creek in South Dakota on December 29, 1890, resulted in the deaths of perhaps 300 Sioux men, women, and children. The massacre at Wounded Knee was the last major battle of the Indian Wars of the late 19th century.

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porter is writing economic history because he is focusing on the cost of developing vaccines.