Between 500 and 1500, the civilizations of mesoamerica and the

a.) ran similar regional economics controlled by the state
b.) created the largest long-distance trade networks in the americas
c.) had little to trade with each other because both regions had the same resources
d.) seem to have had little direct contact with each other

The civilization of the Meso Americans and the Andes created a largest long distance trade network in the Americas

Explanation:

These civilization compromised one of the oldest and the indigenous form of complex culture in the parts of Mexico and Central America prior to the Spanish exploration

These cultures and their trade route extended beyond the limits and it extended to the various other parts the Andean civilization is also one of the most ancient known civilization.Their culture spread across the continents and it marked the trade route between the countries and America

D. seem to have had little direct contact with each other

Explanation:

yellow fever and other tropical diseases

honestly you should get that checked out because it really isn't normal