How did the physical features of East Asia affect the route of the Silk Road

The geography of the Silk Roads then is a complex interaction between the physical and climate zones of mountain, steppe or grasslands, and river valleys and oases which often are bounded by uninhabitable desert. Thus populations could be dispersed (in the grasslands) or concentrated in the oases and river valleys. The Silk Road extended approximately 6,437 kilometers (4,000 miles) across some of the world's most formidable landscapes, including the Gobi Desert and the Pamir Mountains. Many routes were needed for trade to be more accessible.

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explanation:

genetics is the study of how dna works, the methodologies defining the new recent technologies allow scientist to have a panoramic view of the entire dna landscape, especially how genomes interact with their environment, including off course, factors outside their organisms.

thus is very possible the existence of both scenarios, where populations of isolated individuals have different genetic traits, and share traits related to genetic mutation, due rats can easily travel overseas using human transport channels. so scientists could get a vast number of data, including human interaction, evolution of rodents, health development, spread of infections, development of new organisms, how genomes evolve in different environments and so on.