Out of all the challenges that the United States faced during Jefferson's administration, which one do you feel is the most serious?

1807 embargo.

Explanation:

The reason for the embargo is the effort to weaken France and Great Britain during the Napoleonic wars. The reason for the prohibition on European goods is a violation of the neutral states of the United States in the war, by depriving their merchants of their products. President Thomas Jefferson suggested Congress acted as a trade war, not a military retaliation.

The embargo was to stop the looting of American ships by Britain and France. The blockade has at the same time undermined the belief of American citizens that their government can enforce its laws fairly, and reinforces the idea among America's enemies that its republican form of government is unprofitable and inefficient. The embargo was revoked in March 1809. A large number of local merchants were outraged by the law.

yellow fever and other tropical diseases

interdependence is when all participating groups and individuals depend on each other. if you depend on one anothers goods, you end up trading in order to get the items you're looking for. (for ex: if i have food and you have water, we trade in order to depend on each other to live)