Definition: This disease, which attacks the natural defense systems of humans, burst onto the scene in the 1980s.

Aids.

Explanation:

AIDS epidemic during the 1980's had a substantial impact on the people and the economy of several nations. The first case of AIDS was reported in the year 1981 in the United States. This number hugely increased during the decade of 1980's and came to an end in the later phase of 1990's. The greatest impact of the epidemic could be seen among men, who had s-ex with men and among minorities.

the federalist party which advocated strong centralization dominated the united states government till 1800. so 1800 election transformed the power from one party to another party for the first time and was thus a turning point in american history. so jefferson called it "revolution of 1800".

explanation:

the american colonists were happy with their vicorty, but the french were mad and the french and indians were not alies, and neither were the french and colonist. i think,