Why was the location of Cuba so significant during the Cuban missile crisis?

Cuba is located 90 miles from the coast of Florida and mid-range communist missiles could reach U. S. cities from there.

Cuba is located between the Pacific Ocean and the Gulf of Mexico and mid-range communist missiles could reach California from there.

Cuba is located in the Red Sea and mid-range communist missiles could reach Louisiana from there.

Cuba is located in the Pacific Ocean and mid-range communist missiles could hit targets in California from there.