How did the Indian Removal Act impact the Cherokee and Seminole nations?

When the Indian Removal Act was in effect the 5 Indian tribes (The Choctaw, Creek, Chickasaw, Cherokee, and the Seminole) were forced to move west of the Mississippi River to current day Oklahoma by walking in lines chained to each other. This was called the Trail of Tears. By 1840 tens of thousands of Indians were driven off their land.

Explanation:

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the answer is a) james madison.