In Modern America, what events could possibly lead to the secession of states from the union? Be specific and include multiple scenarios if you can.

Disagreements over federal laws, goverment and matters, are the most likely cause for secession in Modern America.

For example, if the federal government passes a law that taxes certain economic activities very high, and these activities are very important for a particular state, that particular state could start a secessio process, although such process would not be likely to succeed.

Another possibility is if a state inhabitants simply become nationalist and start separatist movements.

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