Which of the following challenges did La Salle and his colonists encounter when they tried to set up a French colony at the mouth of the Mississippi river? i. They were attacked by the Iroquois.
ii. La Salle was killed in a storm on the journey to North America.
iii. They overshot their destination.
iv. The colonists were plagued by disease and starvation.

A. i. and iv. only
B. iii. and iv. only
C. i., ii., and iii. only
D. i., ii., iii., and iv.