How did the proclamation of 1763 change the relationship between the colonists and British

After Britain won the Seven Years' War and gained land in North America, it issued the Royal Proclamation of 1763, which prohibited American colonists from settling west of Appalachia. The Treaty of Paris, which marked the end of the French and Indian War, granted Britain a great deal of valuable North American land., So the colonists and Britain their relationship have changed because the colonists cannot settle west of Appalachia