Why were people living in port cities some of the earliest victims of the plague? The plague spread along sea trade routes People fleeing the plague traveled on the sea.
The germs for the plague lived in ocean water.
People in port cities ate fish affected by the plague

Along sea trading lines, the plague spread.

Explanation:

The disease traveled along trading lines, the closer you came to a commercial road, the quicker it was to get sick. The gap across each epidemic of the epidemic and its nearest trading route was then determined and its association with the cumulative count within each breakout point was approximate.

the first action that caused many creek indians to turn against william mcintosh was when mcintosh a) supported the united states during the creek war of 1813–1814. b) attempted to stop the sale of creek land to the u.s. government. c) seized control of over 1,000 acres of land belonging to the creeks.