The voyages of Columbus in 1492 led directly to a period characterized by (A) the expansion of control by the most warlike states of the Americas.
(B) Amerindians attempting to flee the Americas in the face of European aggression.
(C) increased European interest in transoceanic travel and trade.
(D) incursions by dominant Amerindian tribes into tributary states.

Can someone please help me, I don't understand this question.