How did native Americans respond to the loss
of land from white settlement of the Great Plains?

They killed soldiers, attacked and destroyed wagon trails

"Native Americans resisted by attacking wagon trains, stagecoaches, and ranches. Occasionally an entire group would go to war against nearby settlers and troops. The first major clash on the Plains began in 1862, when the Sioux people in Minnesota launched a major uprising."

Comes straight from the book the question i asked in, on page 426

the correct answer is:

true

i am an online student and after i submit my quizzes, it gives me the correct answers to any that i may have missed. the answer to this question is true