The indigenous populations of the new world were greatly reduced due to
a. slavery
b. disease
c. migration

B. Disease

Explanation:

Among several factors, epidemic diseases were by far the largest cause of population decline among Native Americans. Diseases began to kill huge numbers of indigenous Americans shortly after the Europeans and Africans began to reach the new world. The most devastating disease was smallpox, but other deadly diseases such as typhus, measles, influenza, bubonic plague, mumps, yellow fever and pertussis massacred the natives.

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