What anti-federalist argument does madison counter in this essay?

Sea exploration became important during the late middle ages because europeans most likely wanted to

How did disease impact the human death toll during this time period? disease killed more people than combat during this time. disease steadily increased as the war hospitals were attacked. improvements in medical technology decreased illness overall. disease was a small but significant contributor to deaths at this time.

Which best represents the view of the southern delegates at the constitutional convention