What long-term consequences did the Columbian exchange have on native peoples in the Americas?

Physical and psychological stress, including mass violence, compounded their effect. The impact was most severe in the Caribbean, where by 1600 Native American populations on most islands had plummeted by more than 99 percent. Across the Americas, populations fell by 50 percent to 95 percent by 1650.

Explanation:

A. It forced native kingdoms to form joint-stock companies that weakened their economies.

B. It brought farming techniques to the Americas for the first time.

C. It resulted in disease outbreaks that devastated native populations.

D. It helped native empires to expand their territories using gunpowder weapons.

Explanation:

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which empire had the greatest influence on the history and cultural development of russia?