What enormous area of land was anchored to the south by the city of new orleans

How  did spanish  power increaseunder charles  v and philip ii? in 1519,charles  v inherited a huge empire. he became king of  spain  and was also the heir to the hapsburg empire. during his 42-year reign, philip worked to expand  spanish  influence, strengthen the catholic church, and make his own power absolute. hope this !

Ithink it is 4. making colonies. 

The have over 100 billion people in america

Idon't know the answer is