What resulted in the formation of the republican party?

The issue of slavery was a major underlying issue to the formation of the Republican party.

On May 20th, 1854,  a group of politically- minded former Whigs met in Ripon , Wisconsin to talk about the possibility of forming a new political party that would focus on preventing the spread of slavery in the Western territories. The idea  took off and on June 6th 1854, over 10,000 people  gathered in Jackson, Michigan to establish the new party and thus the Republican party was born.

powers  are  denied  to the  national governmentin three distinct ways: some  powers, such as the  power  to levy duties on exports or prohibit the freedom of religion, speech, press, or assembly, are expressly  denied  to the  national government  in the  constitution.