An effect of english settlement in the carolinas was the migration of the:

The Tuscarora people, a Native American clan of hemp gatherers that used to occupy the area known these days as "The Carolinas" until European settlers and colonies arrived; then in the Tuscarora War around 1700s lots of them were killed and slaved by the English army, aside been exposed to infectious diseases from European contact, thus they migrated to what these days is the state of New York.

Explanation:

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cherokee and arikara